
You can now order your T-SPOT®.TB test through Quest Diagnostics®
About the T-SPOT.TB test
The T-SPOT.TB test is a unique, single-visit blood test for tuberculosis (TB) screening, also known as an interferon gamma release assay (IGRA). The cell enumeration technology in the proprietary T-SPOT.TB test allows clinicians to confidently screen and detect TB infection.1
The T-SPOT.TB test advantage

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Accurate across patient populations2
The only TB test with sensitivity and specificity exceeding 95% in clinical studies – including the immunocompromised – which may include:
- Rheumatoid arthritis, diabetes, HIV, chronic renal failure, cancer, advanced age and many other conditions
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Consistent results3,4
98.9% concordance and invalid rate < 1%
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One tube with no refrigeration2
Standard phlebotomy, no on-site pre-analytical steps

Interferon-gamma release assay
The T-SPOT.TB test is a T cell based interferon-gamma release assay (IGRA), designed to enable accurate results across patient populations, even in patients with a weakened immune status. The T-SPOT.TB test separates T cells from whole blood and standardizes the number of these cells in each patient test well. The T-SPOT.TB test also washes the cells to remove potentially interfering substances that can affect test results.2 The inclusion of these steps in the T-SPOT.TB test design mitigates the risk of false or invalid test results.